Wednesday, 18 December 2024 18:41

New insights into ADHD treatments for adults

Attention deficit hyperactivity disorder (ADHD) Attention deficit hyperactivity disorder (ADHD) Pixabay

Attention deficit hyperactivity disorder (ADHD) is often associated with childhood, but its symptoms frequently persist into adulthood. A recent study published in Lancet Psychiatry evaluated the effectiveness of various pharmacological and non-pharmacological treatments for adult ADHD. The findings highlight both promising options and significant knowledge gaps that require further investigation.

Table of contents:

Core symptoms and prevalence of ADHD

ADHD affects approximately 5-7% of children and 2.5% of adults globally. The disorder stems from impaired executive function and self-regulation skills. These deficits manifest as inattention, hyperactivity, and impulsivity, leading to challenges in organization, concentration, and impulse control. Diagnosing ADHD involves evaluating whether symptoms are persistent, pervasive, and inappropriate for a person’s developmental stage, as well as assessing their impact on daily life.

Dr. Samuele Cortese, professor at the University of Southampton, emphasized that ADHD is a serious condition with potential implications for mental and physical health, social interactions, and overall quality of life.

Effectiveness of pharmacological treatments

Stimulant medications such as lisdexamfetamine and methylphenidate, as well as atomoxetine, showed the most effectiveness in treating ADHD symptoms. These treatments outperformed placebos in a short-term 12-week period, based on clinician and patient evaluations. However, some medications were discontinued due to adverse effects, with emotional dysregulation responding better to stimulants and atomoxetine than to placebos.

Despite these findings, medications did not show significant benefits for executive functioning or overall quality of life compared to placebos. This highlights the need for a broader approach to managing ADHD symptoms.

Insights into nonpharmacological approaches

Nonpharmacological treatments such as cognitive behavioural therapy (CBT), mindfulness, psychoeducation, and transcranial direct current stimulation were also examined. These methods were reported as effective by clinicians but not consistently recognized by patients. While they may not directly target core symptoms, these approaches help individuals develop coping skills and strategies to manage ADHD’s impact on their lives.

Dr. Margaret Sibley from the University of Washington highlighted that these interventions often improve self-efficacy, autonomy, and psychological well-being, which were not primary outcomes in this study. This mismatch underscores the complexity of measuring ADHD treatment success.

Future research needs and recommendations

The study reveals significant gaps in understanding long-term treatment outcomes for adult ADHD. Most reviewed trials lasted less than 12 weeks, limiting insights into sustained effectiveness. Additionally, combining pharmacological and nonpharmacological treatments — a common practice in ADHD management — was not sufficiently explored.

Experts, including Dr. Edoardo G. Ostinelli from Oxford University, stressed the importance of conducting longer studies that evaluate diverse treatment combinations. Personalized approaches, considering individual preferences and symptom variability, are critical for effective ADHD management.

Comprehensive ADHD treatment should address more than just core symptoms. By integrating pharmacological and nonpharmacological methods, individuals can develop personalized strategies for managing their condition. As research continues, a deeper understanding of long-term treatment efficacy and tailored interventions will improve outcomes for adults living with ADHD.

source: CTV News

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